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Best Brisket Injection Recipe

Take your brisket to the next level with my Best Brisket Injection Marinade recipe. It enhances flavor and adds moisture to tough cuts of beef. The result is a succulent smoked beef brisket every time.


There is no arguing that beef brisket is a thick, tough cut of meat. However, using an injection marinade is an excellent way to flavor it from the inside. It will ensure the meat remains moist and tender throughout the cooking process.

What is a Brisket Injection Marinade?

An injectable marinade is a thin, flavorful liquid placed into a kitchen-safe meat injector and then inserted into several spots in the meat. You can put together a unique formula, like this Best Brisket Injection marinade, or use the same flavor profile as the rub you’ll be using. You can use an injection marinade in one of two ways.

  • Option 1: Apply the rub and use the injection marinade about 1 hour before the brisket goes on the smoker (as pictured above). 
  • Option 2: When injecting brisket, do not apply the rub. Wrap it tightly in plastic wrap and place it in your refrigerator for up to 12 hours (see photo below). Season your brisket 30-60 minutes before it enters the smoker.
Best Brisket Injection

Ingredients for Best Injection Marinade:

  • Beef stock: I suggest using Minor’s Beef Base
  • Whiskey
  • Worcestershire sauce
  • Brown sugar (optional)
  • Soy sauce
  • Salt (optional)
  • Onion powder (sub with garlic powder if preferred)
  • Black pepper

Making a Brisket Injection Marinade:

  • Combine beef base with water according to package instructions.
  • Add beef broth to a small saucepan with the remaining marinade ingredients.
  • Simmer mixture over medium heat until sugar and salt have dissolved, about 3 minutes.
  • Remove saucepan from heat. and let the mixture cool for 30-40 minutes before using.

How to inject Brisket

  • First, ensure there are no clumps of spices or herbs in your injection marinade that could clog up your injector and create a mess. Pour marinade through a kitchen strainer if needed.
  • Draw some of the marinade solution into the syringe by submerging the needle into the marinade and then pulling back the plunger. Then, inject a little bit into the meat.
  • Please note that the marinade will travel along the grain of the meat, so use the lines of muscle to guide where to inject.
  • There will be some flow back, especially if you inject too much solution. Blot it away with paper towels, and repeat the process in several spots over the whole brisket.

How to make a spritz with leftover marinade

  • If you have 1/2 cup or more of leftover brisket injection marinade, pour it into a pot and bring it to a boil on your stovetop. 
  • Once it reaches boiling point, reduce the heat and let it simmer on low for 5-6 minutes. Doing this will help kill off any bacteria it may have encountered during the syringe-to-meat transfer. 
  • After simmering, remove the pot from the heat and allow the solution to cool for 5-7 minutes. 
  • Once cooled, pour the solution into a spray bottle and use it as a barbecue spritz for the smoked brisket. 

Thoughts on liquid smoke

There is no need to use liquid smoke if the brisket is already in the smoker. However, if oven roasting or using a gas unit, add a little bit to to the brisket injection marinade. Remember that liquid smoke is an all-natural product that passes real wood smoke through water, then distills it.

Need Help choosing the right brisket? See my Brisket Buying Guide for more information.

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Beef Brisket Injection

Best Brisket Injection Marinade

Some people don’t bother injecting briskets. This is a mistake. A good meat injection imparts flavor and liquid into your brisket before it hits the grill. This is my best brisket injection, and I combine a little sweet and some savory to bring out the beefiness of the brisket.
4.62 from 149 votes
Print Pin Rate
Course: Marinades/Brines
Cuisine: American BBQ
Keyword: brisket injection, Injection marinade
Prep Time: 10 minutes
Total Time: 10 minutes
Servings: 1 cup
Calories: 101kcal
Author: Derrick Riches


  • 1 cup beef broth (Minor's Beef Base recommended)
  • 1 tablespoon whiskey
  • 1 1/2 teaspoons Worcestershire sauce
  • 2 teaspoons brown sugar (optional)
  • 1 teaspoon soy sauce
  • 1/2 teaspoon onion powder sub with garlic powder
  • 1/2 teaspoon black pepper
  • 1/4 teaspoon salt (optional)


  • Combine beef base with water according to package instructions.
  • Add beef broth to a small saucepan with the remaining marinade ingredients.
  • Simmer mixture over medium heat until sugar and salt have dissolved, about 3 minutes.
  • Remove saucepan from heat. and let the mixture cool for 30-40 minutes before using.
  • To inject your brisket, lay it out flat. Looking down on the meat, inject into the center of the meat every two inches, working from one end to the other.
    Squeeze in the injector slowly and move to a new location when the liquid starts to leak out a little.
    Work your way through the entire brisket getting a small amount of the solution into as many places as possible.


Calories: 101kcal | Carbohydrates: 11g | Protein: 4g | Fat: 1g | Saturated Fat: 1g | Sodium: 2482mg | Potassium: 248mg | Fiber: 1g | Sugar: 9g | Vitamin A: 13IU | Vitamin C: 1mg | Calcium: 41mg | Iron: 1mg

Looking for a simple, yet great way to make smoked brisket? Try my method How to Make Barbecue Brisket.

Need an Injector for this Brisket Injection Marinade Recipe?

Ofargo Marinade Injector

Ofargo Marinade Injector

The Ofargo Marinade Injector is a classic-style syringe. The marinade is sucked up through the needle and then pushed back into the meat. The needle on this model is large enough that it shouldn’t clog. Still, make sure that your marinade is near water-thin. It is an inexpensive unit that you can purchase for around $10. It is dishwasher safe and durable enough to last for several years. The volume of this injector is small, but it will handle most jobs for a single-family. This plastic injector will hold up to one ounce at a time.

Oklahoma Joes Trigger Marinade Injector

Oklahoma Joe’s Trigger Meat Injector

The Oklahoma Joe’s Trigger Meat Injector is more of a marinade pump than a syringe. Dip the hose end into a container with your marinade, and the trigger mechanism pumps the solution into the meat on both strokes. This will make for faster injecting and is excellent for those that are doing more than a single, small roast. At around $30, you pay a little more, but it can handle a lot more injecting. It will save your hands if you have a lot to do.

Chop's Power Injection System

Chop’s Power Injection System

Doing a lot of brisket injecting? Then this is the system you need. The tank holds a gallon of injection solution. Pump up the pressure and start injecting. It is the system used by caterers and BBQ competition cooks. Easy on the hands, it will allow you to inject at lightning speed. Of course, it costs around $160, so this is really for those who make money on barbecue.

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